(S)-Fmoc-2-amino-3-(2-methylphenyl)propionic acid
Fmoc-2-methyl-L-phenylalanine
CAS: 211637-75-1
Molecular Formula: C25H23NO4
(S)-Fmoc-2-amino-3-(2-methylphenyl)propionic acid - Names and Identifiers
| Name | Fmoc-2-methyl-L-phenylalanine |
| Synonyms | Fmoc-L-2-Methylphe Fmoc-L-2-Me-Phe-OH FMOC-L-2-Methylphe Fmoc-L-2-Methyl-phe-OH Fmoc-L-2-Methylphenylalanine Fmoc-2-methyl-L-phenylalanine 2-Methyl-L-phenylalanine, N-FMOC protected FMoc-L-2-Me-Phe-OH FMoc-2-Methy-L-Phenylalanine FMoc-2-Methyl-L-phenylalanine FMoc-o-Me-L-Phe-OH (S)-Fmoc-2-amino-3-(2-methylphenyl)propionic acid N-Fluorenemethoxycarbonyl-L-2-Methyl Phenylalanine (S)-2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-3-(o-tolyl)propanoic acid |
| CAS | 211637-75-1 |
| InChI | InChI=1/C24H21NO4/c1-15-8-2-3-9-16(15)14-21(23(26)27)25-24(28)29-22-19-12-6-4-10-17(19)18-11-5-7-13-20(18)22/h2-13,21-22H,14H2,1H3,(H,25,28)(H,26,27)/t21-/m0/s1 |
(S)-Fmoc-2-amino-3-(2-methylphenyl)propionic acid - Physico-chemical Properties
| Molecular Formula | C25H23NO4 |
| Molar Mass | 401.45 |
| Density | 1?+-.0.06 g/cm3(Predicted) |
| Melting Point | 118°C |
| Boling Point | 631.1±55.0 °C(Predicted) |
| Specific Rotation(α) | -45 º (c=1,DMF) |
| Flash Point | 330.8°C |
| Vapor Presure | 2.09E-16mmHg at 25°C |
| BRN | 9157614 |
| pKa | 3.81±0.11(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.664 |
| Physical and Chemical Properties | alpha:-45 o (c=1,DMF) |
(S)-Fmoc-2-amino-3-(2-methylphenyl)propionic acid - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
(S)-Fmoc-2-amino-3-(2-methylphenyl)propionic acid - Introduction
Fmoc-2-methyl-L-phenylalanine(Fmoc-2-methyl-L-phenylalanine) is an amino acid derivative. The following is a description of some properties, uses, preparation and safety information about the compound:
Nature:
- Fmoc-2-methyl-L-phenylalanine is a colorless to pale yellow crystalline solid.
-It is dissolved in organic solvents (such as dimethyl sulfoxide, dichloromethane) can be a transparent solution.
-This compound has good thermal stability and solubility, making it easy to operate in chemical synthesis.
Use:
- Fmoc-2-methyl-L-phenylalanine is a commonly used amino acid derivative, which is widely used in the field of peptide synthesis and protein engineering.
-It can be used in related experiments such as polypeptide chain extension, modification and labeling.
Method:
-There are many ways to synthesize Fmoc-2-methyl-L-phenylalanine, but a common method is through nuclear magnetic resonance (NMR)-guided solid-phase synthesis technology.
-This method usually requires the protection of the side chain of the amino acid (for example, the use of Fmoc protecting group), and then through successive steps of grouping, reaction and deprotection, and finally the target molecule is obtained.
Safety Information:
-The safety of the Fmoc-2-methyl-L-phenylalanine is high, but basic laboratory operation specifications and personal protective measures are still required during the operation.
-When preparing and handling this compound, care should be taken to avoid inhalation, ingestion or contact with skin and eyes.
-During use, try to avoid dust or aerosols.
-It is recommended to operate in a well-ventilated laboratory and wear appropriate personal protective equipment, such as laboratory coats, gloves and glasses.
-In any case, the operation should be strictly based on the safety data sheet of the relevant chemicals, and the laboratory's safe operation procedures should be followed.
Nature:
- Fmoc-2-methyl-L-phenylalanine is a colorless to pale yellow crystalline solid.
-It is dissolved in organic solvents (such as dimethyl sulfoxide, dichloromethane) can be a transparent solution.
-This compound has good thermal stability and solubility, making it easy to operate in chemical synthesis.
Use:
- Fmoc-2-methyl-L-phenylalanine is a commonly used amino acid derivative, which is widely used in the field of peptide synthesis and protein engineering.
-It can be used in related experiments such as polypeptide chain extension, modification and labeling.
Method:
-There are many ways to synthesize Fmoc-2-methyl-L-phenylalanine, but a common method is through nuclear magnetic resonance (NMR)-guided solid-phase synthesis technology.
-This method usually requires the protection of the side chain of the amino acid (for example, the use of Fmoc protecting group), and then through successive steps of grouping, reaction and deprotection, and finally the target molecule is obtained.
Safety Information:
-The safety of the Fmoc-2-methyl-L-phenylalanine is high, but basic laboratory operation specifications and personal protective measures are still required during the operation.
-When preparing and handling this compound, care should be taken to avoid inhalation, ingestion or contact with skin and eyes.
-During use, try to avoid dust or aerosols.
-It is recommended to operate in a well-ventilated laboratory and wear appropriate personal protective equipment, such as laboratory coats, gloves and glasses.
-In any case, the operation should be strictly based on the safety data sheet of the relevant chemicals, and the laboratory's safe operation procedures should be followed.
Last Update：2024-04-09 15:17:55
